In Nazi Germany in 1936 seven men escape from a concentration camp. The camp commander puts up seven crosses and, as the Gestapo returns each escapee he is put to death on a cross. The seventh cross is still empty as George Heisler seeks freedom in Holland.

Successful and well-liked, Dr. Noah Praetorius becomes the victim of a witch hunt at the hands of Professor Elwell, who disdains Praetorius's unorthodox medical views and also questions his relationship with the mysterious, ever-present Mr. Shunderson. Fuel is added to the fire when Praetorius befriends young Deborah Higgins, who has become suicidal at the prospect of having a baby by her ex boyfriend, a military reservist who was called up for service in the Korean War and killed in action.